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| In simplest terms, hyperlipidemia is an elevation of lipids (fats) in the bloodstream. These lipids include cholesterol, cholesterol esters (compounds), phospholipids and triglycerides. They're transported in the blood as part of large molecules called lipoproteins. |
Table summarizing effect of oral lactobacillus sporogenes over 90 days |
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From Avicenna's -Medline Abstract report on the "Short term hypolipidemic effects of oral lactobacillus Sporogenes therapy in patients with primary dyslipidemias" reads as follows: |
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Abstract
Date: 1990 Sep-Oct:
Short term hypolipidemic effects of oral Lactobacillus sporogenes (360 million spores/day) were studied in 17 patients (mean age 45.6 years; males 15, females 2) with type II hyperlipidemia in an open label fixed dose trial. Over a period of 3 months, significant reductions were observed in total cholesterol (330 +/- 55mg to 226 +/- 46 mg%, p less than 0.001) and LDL- cholesterol (267 =/- 58 mg% to 173 =/- 54 mg%, p less than 0.001), The HDL-cholesterol was marginally increased (43.6 =/- 7 mg% to 46.8 =/- 8.9 mg%, p less than 0.05) |
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| There
was no change in serum triglyceride concentration. Total cholesterol/HDL cholesterol and LDL cholesterol/HDL cholesterol
ratios were significantly reduced after treatments (p less than 0.001. No
adverse effect was noted. While the change in serum lipid levels on treatment
was consistent with regard to total and LDL -cholesterol, it was not so
in case of serum triglycerides and HDL- cholesterol. Oral Lactobacillus
Sporogenes therapy may prove to be an important hypolipidemic therapy after
confirmation in larger trials. Mohan JC; Arora R; Khalilulla M. Department of Cardiology, G.B. Pant Hospital, New Delhi |
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